Selected Publications

Mouzakis FL, Khadka LB, Pereira da Silva M, Mottaghy K. Application of Hydrogen in Hemodialysis: A Brief Review with Emphasis on the Quantification of Dissolved H2. In: Slezak J, Kura B. (eds) Molecular Hydrogen in Health and Disease. Advances in Biochemistry in Health and Disease, vol 27. 2024 Springer, Cham.

Mouzakis FL, Kashefi A, Spillner J, Rütten S, Mottaghy K, Hima F. A new approach towards extracorporeal gas exchange and first in vitro results. Biomed Tech (Berl). 2023 Nov 7.

Khadka LB, Mouzakis FL, Kashefi A, Hima F, Spillner JW, Mottaghy K. Blood Gas Parameters and Acid–Base Balance during Extracorporeal Lung Support with Oxygenators: Semi-Empirical Evaluation. Mathematics. 2023; 11(19):4088.

Hima F, Saunders A, Kashefi A, Mouzakis F, Mottaghy K, Spillner J, Zayat R, Kalverkamp S. In vitro evaluation of the performance of an oxygenator depending on the non-standard gas content of the inlet blood with special regard on CO2 elimination. Perfusion. 2023 Sep 22.

Hima F, Kalverkamp S, Kashefi A, Mottaghy K, Zayat R, Strudthoff L, Spillner J, Mouzakis F. Oxygenation performance assessment of an artificial lung in different central anatomic configurations. Int J Artif Organs. 2023 May;46(5):295-302.

Tabesh H, Poorkhalil A, Akbari H, Rafiei F, Mottaghy K. Phenomenological characterization of blood’s intermediate shear rate: a new concept for hemorheology. Phys Eng Sci Med. 2022 Dec;45(4):1205-1217.

Mouzakis FL, Khadka LB, Pereira da Silva M, Mottaghy K. Quantification of dissolved H2 and continuous monitoring of hydrogen-rich water for haemodialysis applications: An experimental study. Int J Artif Organs. 2022 Jan 25:3913988211070588.

De Lazzari B, Iacovoni A, Mottaghy K, Capoccia M, Badagliacca R, Vizza CD, De Lazzari C. ECMO Assistance during Mechanical Ventilation: Effects Induced on Energetic and Haemodynamic Variables. Comput Methods Programs Biomed. 2021 Feb 14;202:106003.

Stegmayr B, Willems C, Groth T, Martins A, Neves NM, Mottaghy K, Remuzzi A, Walpoth B. Arteriovenous access in hemodialysis: A multidisciplinary perspective for future solutions. Int J Artif Organs. 2021 Jan;44(1):3-16.

Poorkhalil A, Mouzakis F, Kashefi A, Mottaghy K. The course of hematocrit value along the length of a dialyzer’s fiber: Hemoconcentration modeling and validation methods. Int J Artif Organs. 2019; 42(9): 482‐489.

Tran L, Mottaghy K, Arlt-Körfer S, Waluga C, Behbahani M. An experimental study of shear-dependent human platelet adhesion and underlying protein-binding mechanisms in a cylindrical Couette system. Biomed Tech (Berl). 2017 Aug 28;62(4):383-392.

Poorkhalil A, Amoabediny G, Tabesh H, Behbahani M, Mottaghy K. A new approach for semiempirical modeling of mechanical blood trauma. Int J Artif Organs. 2016; 39(4): 171‐177.

Tabesh H, Elahi Z, Amoabediny G, Kashefi A, Mottaghy K. A Perspective on the Development and Clinical Application of Oxygenators: Past, Present and Future. Journal of Mazandaran University of Medical Sciences (JMUMS).2015; 25(121)

Tabesh H, Amoabediny G, Rasouli A, Ramedani A, Poorkhalil A, Kashefi A, Mottaghy K. Simulation of blood oxygenation in capillary membrane oxygenators using modified sulfite solution. Biophysical chemistry. 2014; 195, 8-15.

Khachab A., Tabesh H., Kashefi A., Mottaghy K. Novel Concept For Pure Diffusive Capillary Membrane Oxygenators: Silicone Hollow Sphere (SiHSp) Fibers. ASAIO J. 2013;59(2):162-8.

Salehi-Nik N, Amoabediny Gh, Pouran B, Tabesh H, Shokrgozar MA, Haghighipour N, Khatibi N, Anisi F, Mottaghy K, Zandieh-Doulabi B. Engineering Parameters in Bioreactor’s Design: A Critical Aspect in Tissue Engineering. BioMed Research International. 2013.

Hermann S., Kashefi A., Mottaghy K., Reilly R. The Ballistocardiogram as a Contactless Registration Method for Cardiovascular Parameters. Int J Artif Organs, 36(8), 563.

Verkerke GJ, van der Houwen EB, Broekhuis AA, Bursa J, Catapano G, McCullagh P, Mottaghy K, Niederer P, Reilly R, Rogalewicz V, Segers P, Verdonschot N. Science versus design; comparable, contrastive or conducive? Journal of the Mechanical Behavior of Biomedical Materials Volume 21. 2013; 195–201.

Tabesh H, Amoabediny Gh, Poorkhalil A, Khachab A, Kashefi A, Mottaghy K. A theoretical model for evaluation of the design of a hollow-fiber membrane oxygenator. Int J Artif Organs. 2012; 15: 347-356.

Khachab A., Oedekoven B., Hahn A., Mottaghy K. Effect of pulmonary surfactant on O2 diffusion in a physical Model. Int J Artif Organs, 33(7), 423.

Mottaghy K., Oedekoven B., Hassoun H., Hahn A. Oxygen Diffusion Through Different Liquid Layers with and Without Surfactant in a Physical Model. Acta Physiologica, 195(669), 5.

Tabesh H, Amoabediny GH, Salehi Nik N, Heydari M, Yousefifard M, Ranaei Siadat SO, Mottaghy K. The role of biodegradable engineered scaffolds seeded with Schwann cells for spinal cord regeneration. Neurochemistry International Journal. 2009; 54:2, 73-83. doi: 10.1016/j.neuint.2008.11.002

Fischer H, Luk M, Oedekoven B, Telle R, Mottaghy K. Hemocompatibility of high strength oxide ceramic materials: An in vitro Study. Journal of Biomed Materials Research Part A. 2007; 982-986. doi: 10.1002/jbm.a.31119

Orfao SMC, Jank G, Mottaghy K. A new mathematical approach to modelling thrombin generation. Int J Artif Organs. 2006 ; 29(7). doi : 10.1177/039139880602900710

Kopp R, Bensberg R, Kashefi A, Mottaghy K, Rossaint R, Kuhlen R. Effect of hirudin versus heparin on hemocompatibility of blood contacting biomaterials: An in vitro study. Int J Artif Organs. 2005; 28(12), 1272-1277. doi: 10.1177/039139880502801211

Salimi S., Henseler A., Motaghy K.: Non Equilibrium O2-Dissociation Curves (ne-ODC): Effect of pO2, Shear Rate and Haematocrit. Int J Artif Organs, 28 (9).

Körfer S, Klaus S, Mottaghy K. Application of Taylor Vortices in Hemocompatibility Investigations. Int J Artif Organs. 2003; 26(4): 331-338. doi : 10.1177/039139880302600408

Kopp R, Mottaghy K, Kirschfink M. Mechanism of Complement Activation during Extracorporeal Blood Biomaterial Interaction: Effects of heparin coated and uncoated surfaces. ASAIO Journal. 2002; 48: 598-605. doi: 10.1097/00002480-200211000-00005

Klaus S, Körfer S, Mottaghy K, Reul H, Glasmacher B. In vitro blood damage by high shear flow: Human versus porcine blood. Int J Artif Organs. 2002 ; 25(4): 306-312. doi : 10.1177/039139880202500409

Eitschberger S, Henseler A, Krasenbrink B, Oedekoven B, Mottaghy K. Investigation on the Ability of an Ultrasound Bubble Detector to Deliver Size Measurements of Gaseous Bubbles in Fluid Lines by Using a Glass Bead Model. ASAIO Journal. 2001; 47: 18-24. doi: 10.1097/00002480-200101000-00006

Radke A, Mottaghy K, Goldmann Ch, Khorram-Sefat R, Kovacs B, Janssen A, Klosterhalfen B, Hafemann B, Pallua N, Kirschfink M.C1 Inhibitor Prevents Capillary Leakage after Thermal Trauma. Critical Care Med. 2000; 28(9): 3224-32. doi: 10.1097/00003246-200009000-00018

Metzler V, Lehmann T, Bienert H, Mottaghy K, Spitzer K. Scale-independent shape analysis for quantitative cytology using mathematical morphology. Computers in Biology and Medicine. 2000; 30: 135-151. doi: 10.1016/S0010-4825(00)00003-2

Graf J, Königs B, Mottaghy K, Janssens U. In vitro validation of gastric air tonometry using perfluorocarbon FC-43 and 0.9% sodium chloride. British Journal of Anaesthesia. 2000; 84(4): 497-9. doi: 10.1093/oxfordjournals.bja.a013477

Keldenich S, Kopp R, Kirschfink M, Klein B, Henseler A, Thelen H, Oedekoven B, Mottaghy K. Application of a New Dynamic Flow Model for Investigating the Biocompatibility of Modified Surfaces. ASAIO Journal. 2000; 46: 134-141. doi: 10.1097/00002480-200001000-00030

Henseler A, Oedekoven B, Andersson C, Mottaghy K. Entwicklung eines modifizierten “Chandler-Loop-Systems” zur Evaluierung der Biokompatibilität von ECC-Schläuchen. Kardiotechnik. 1999; 3: 66-69

Metzler V, Bienert H, Lehmann T, Mottaghy K, Spitzer K. A novel method for quantifying shape deformation applied to biocompatibility testing. ASAIO Journal. 1999; 45: 264-271.doi: 10.1097/00002480-199907000-00004

Khorram-Sefat R, Goldmann CH, Radke A, Lennartz A, Mottaghy K, Afify M, Küpper W, Klosterhalfen B. The Therapeutic Effect of C1-Inhibitor on Gut-Derived Bacterial Translocation After Thermal Injury. Shock. Europe PMC. 1998; 9/2: 101-108. doi: 10.1097/00024382-199802000-00005

Eitschberger S, Krasenbrink B, Henseler A, Oedekoven B, Mottaghy K. Ein optimiertes Verfahren zur Beurteilung des Rückhaltevermögens arterieller Filter für gasförmige Emboli. Kardiotechnik. 1996; 4: 108-112

v. Neuerburg J, Haupt-Pichler A, Katterbach FJ, Eilers R, Sieß T, Buro K, v. Pichler C, Mottaghy K, Günther RW. Bestimmung der Effektivität perkutaner Kavafilter: Experimentelle Untersuchungen. Fortschr. Röntgenstr. 1996; 164,4: 331-337. Georg Thieme Verlag Stuttgart – New York

Radke A, Kirschfink M, Goldmann Ch, Mottaghy K, Hettich R. The Protective Effect of C1-Inhibitor on Thermal Trauma: First Results from an Animal Study. Biomedical Progress. 1996; 9/1:10.

Mottaghy K. Extracorporeal Lung Support with Heparinized Systems: An Overview on Experimental Investigations. ed: C. Roussos. 8th European Congress of Intensive Care Medicine. 1995 October 18-22. Athens

Beer AM, Dickgreber NJ, Mottaghy K. Untersuchungen zum Gasaustausch unter der Geburt mit besonderer Berücksichtigung der intraerythrozytären Sauerstoff-Sättigung. Hypoxische Gefährdung des Fetus sub partu. 1994. R. Knitza, Steinkopff Verlag. Darmstadt

Kirschfink M, Kovacs B, Mottaghy K. Extracorporeal circulation: In vivo and in vitro analysis of complement activation by heparin-bonded surfaces. Circulatory Shock. Europe PMC. 1993; 40:221-226

Assmann R, Heidelmeyer CF, Trampisch HJ, Mottaghy K, Versprille A, Sandmann W, Falke KJ. Right ventricular function as¬sess¬ed by thermodilution technique during apnea and mechanical ven¬ti¬lation. Critical Care Medicine. Europe PMC. 1991; 19/6: 810-817.doi: 10.1097/00003246-199106000-00014

Mottaghy K, Oedekoven B, Pöppel K, Kovacs B, Kirschfink M, Bruchmüller K, Kashefi A, Geisen C. Heparin-coated versus non-coated surfaces for extra¬cor¬po¬re¬al circulations. Intern. J. Artif. Organs. 1991; 14: 721-728. doi: 10.1177/039139889101401108

Hoffmann BH, Böhm SH, Morris AH, Simon B, Mottaghy K. In vivo demonstration of Haldane Effect during extracorporeal gas exchange. Intern. J. Artif. Organs. 1991; 14/11: 703-706. doi: 10.1177/039139889101401105

Mottaghy K. Measurement of arterial O2-content with galvanic cells. The Oxygen Status of Arterial Human Blood. 1991. eds: R. Zander and F. Mertzlufft. Verlag S. Karger, Basel, München

Jüngling E, Dautzenberg R, Mottaghy K, Kammermaier H. Ein neues Meßgerät zur schnellen Bestimmung des Sauer¬stoff¬gehaltes im Blut und anderen Biofluiden. Biomed. Technik, 35 (Ergänzungsband). 1990; 92-93. doi: 10.1515/bmte.1990.35.s3.92

Geisen C., Mottaghy K., Scheffen I., Kaufmann P.: Effect Of Long-Term Hypoxia On Oxygen Transport Properties of Blood In Pregnant Guinea Pigs. In: Oxygen Transport To Tissue XII. Editors: J.Piiper et al. Plenum Press, New York.

Scheffen I, Kaufmann P, Philippens L, Leiser R, Geisen C, Mottaghy K. Alterations of the fetal capillary bed in the guinea pig placenta following long-term hypoxia. Oxygen Transport to Tissue XII. 1990. eds: J.Piiper, Goldstick T.K., Meyer M. Springer. Boston. doi: 10.1007/978-1-4684-8181-5_89

Kashefi A, Oedekoven B, Mottaghy K. Untersuchungen über die Gasaustauschkapazität von Polypropylenmembran-Oxygenatoren unter standardisierten in vitro Bedingungen. ECC International Band 2. 1990

Mottaghy K, Oedekoven B, Starmans H, Müller B, Kashefi A, Hoffmann B, Böhm S. Technical aspects of plasma leakage prevention in microporous capillary membrane oxygenators. ASAIO Trans. 1989; 35/3: 640-643.doi: 10.1097/00002480-198907000-00154

Mottaghy K, Oedekoven B, Pöppel K, Bruchmüller K, Kovacs B, Spahn A, Geisen C. Heparin free long-term extracorporeal circulation using bioactive surfaces. ASAIO Trans. 1989; 35: 635-637. doi: 10.1097/00002480-198907000-00152

Mottaghy K, Oedekoven B, Schaich-Lester D, Pöppel K. Non heparin and heparin bonded systems for ECCO2-R: An experimental study. Neonatal and Adult Respiratory Failure. Mechanisms and Treatments. 1989; pp.209-220. ed.: J.P. Gille. Edition Scientifiques Elsevier

Mottaghy K, Oedekoven B, Schaich-Lester D, Pöppel K, Küpper W. Application of surfaces with end point attached heparin to ex¬tracorporeal circulations with membrane lungs. ASAIO Trans. 1989;35: 146-152. doi: 10.1097/00002480-198904000-00006

Klein MD, Arensman RM, Weber TR, Mottaghy K, Langer R, Nolte SH. Pediatric ECMO. Directions for new developments. ASAIO Trans. 1988; 34-4: 978-985

Mottaghy K. Messung der arteriellen O2-Konzentration mit galvanischen Zellen. Der Sauerstoff-Status des arteriellen Blutes. 1988; pp.207-215. R. Zander und F. Mertzlufft. Verlag S. Karger Basel

Mottaghy K, Schaich-Lester D, Lester A, Oedekoven B, Assmann R. Long-term extracorporeal CO2-removal in sheep for up to 7 days using capillary fiber membrane oxygenators. ASAIO Trans. 1987;33: 565-569

Mottaghy K, Oedekoven B, Bey R, Schaich-Lester D, Starmans H, Schmid-Schönbein H. Aspects physiologiques de l’elimination extracorporelle du CO2 chez le chien et le mouton en vue d’application cliniques. Innovation et Technologie en Biologie et Medicine 7 numero special. 1986; pp.55-67. eds: A. Lautier and J.P. Gille. Über¬setzung von [30] auf Veranlassung der Herausgeber

Mottaghy K, Oedekoven B, Bey R, Schmid-Schönbein H. Extracorporeal anticoagulation using a serine protease inhibitor in hemodialysis in sheep. Trans. Am. Soc. Artif. Int. Organs 31. 1985; 534-536

Mottaghy K, Bey R, Oedekoven B, Schaich-Lester D, Schmid-Schönbein H. Extracorporeal CO2-removal : Pulmonary and extracorporeal equilibria in dogs and sheep. Europ. Journ. Applied Physiology 54: 1985; 546-553. doi: 10.1007/BF00422967

Mottaghy K, Hanse HJ. Effect of combined shear, secondary flow and axial flow of blood on oxygen uptake. Chem. Eng. Communications. 1984; 36: 269-279. doi: 10.1080/00986448508911259

Oedekoven B, Bey R, Mottaghy K, Schmid-Schönbein H. Gabexate Mesilate (FOY) as an anticoagulant in extracorporeal circulation in dogs and sheep. Thromb. Haemost. 1984; 52-3: 329-332

Mottaghy K, Haest CWM, Cremer J, Derissen W. Oxygen uptake into the sheared flowing blood: Effects of red cell membranes and haematocrit. Oxygen Transport to Tissue-V. 1984; pp.175-185. eds: D.W. Lübbers, H. Acker, E. Leniger-Follert and T.K. Goldstick. Plenum Publishing Corp. New York. doi: 10.1007/978-1-4684-1188-1_11

Bey R, Mottaghy K, Oedekoven B, Schmid-Schönbein H. Prostacyclineinsatz im extrakorporalen Kreislauf an Kaninchen bei gleichzeitiger Reduktion der Heparindosen. Kardiotechnik. 1983; 6-2:67-71

Motthaghy K, Haest CWM, Schleuter HJ. Effect of red cell rigidity on gas transport by sheared flow¬ing blood. Chem. Eng. Communications. 1981; 15: 157-167. doi: 10.1080/00986448208911066

Mottaghy K, Hahn A. Interfacial tension of some biological fluids: A comparative study. Journ. Clinical Chemistry and Laboratory Medicine (CCLM). 1981; 19: 267-271. doi: 10.1515/cclm.1981.19.5.267

Heinsen H, Mottaghy K, Frömel M. Pulmonary and systemic embolism after deliberate intravenous fluorocarbon administration. Virchows Arch A Pathol Anat and Histol. 1980; 386: 331-341. doi: 10.1007/BF00427302

Mottaghy K, Frömel M, Driessen G, Schnittler HJ, Bey R. Intravital microscopical model to study the influence of extracorporeal pumping on the perfusion of microcirculation. Proc. Eur. Soc. Artif. Organs 7. 1980; 274-278

Wurzinger LJ, Baldauf W, Tobias E, Mottaghy K. Species differences in platelet aggregation with special reference to heparin as anticoagulant. Basis Aspects of Blood Trauma. 1979; pp.80-97. eds: H. Schmid-Schönbein, P. Teitel. Martinius Nijhoff Pub. The Hague Boston. London. doi: 10.1007/978-94-009-9337-2_5

Mottaghy K, Zander M, Busch L. Bluttraumatisierung in Oxygenatoren unter standardisierten Bedingungen am Beispiel eines Bubble-Oxygenators. Biomedizinische Technik 23. 1978; 124-125. doi: 10.1515/bmte.1978.23.s1.248

Mottaghy K, Driessen G, Zander M, Kreisel C, Mendler N, Schmid-Schönbein H. The floating-droplets oxygenator: Developments using fluorocarbons with coaxial rotating cylinders. Trans. Am. Soc. Artif. Intern. Organs. 1977; 23: 464-468

Mottaghy K, Schumacher E, Schmid-Schönbein H. A new blood pumping method: The gravity pump. Proc. Eur. Soc. Artif. Organs IV. 1977; 593-599

Mottaghy K, Mendler N, Schmid-Schönbein H, Schröck R, Sebening F. A new type of fluorocarbon liquid oxygenator. Eur. surg. Res. 1976; 8: 196-203. doi: 10.1159/000127865